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/ Olfactory receptor-like genes are located in the human major histocompatibility complex

Olfactory receptor-like genes are located in the human major histocompatibility complex

W Fan 1 , Y C Liu, S Parimoo, S M Weissman

Abstract

The murine major histocompatibility complex (MHC) includes sequences that are responsible for haplotype-specific odor types that, in turn, influence mating preference. We report that there are several olfactory receptor genes or pseudogenes in the Class I region of the human MHC. At least one of these genes is intact, appears to encode an mRNA, and is quite homologous to a previously reported murine olfactory receptor.

Summary of the Study by SinglePheromones.com:

In the genes of mice, information about the ideal scent of a partner (the most genetically dissimilar) is encoded. These genes are very similar to human genes.

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